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Search Results for " kras 1 "

70

抑制剂 & 化合物

1741

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40272	KRAS mutant protein inhibitor 1
	KRAS mutant protein inhibitor 1 is a KRAS mutant protein inhibitor for potential treatment in cancer.
T9674	KRAS G12D inhibitor 1
	KRAS G12D inhibitor 1 (例 243) 是一种KRAS G12D 抑制剂，对KRAS G12D 介导的 ERK 磷酸化的IC50值为0.8 nM。
T11776	KRas G12C inhibitor 1	Ras	GPCR/G Protein; MAPK
	KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.
T8418	DCLK1-IN-1	Others	Others
	DCLK1-IN-1 是选择性的、体内相容的双皮质素样激酶1DCLK1激酶结构域化学探针。它抑制 DCLK1 和 DCLK2 激酶。它具有低毒性，可以研究 DCLK1 的生物学特性，确定其在肿瘤中的作用，如 DCLK1+胰腺导管腺癌。
T77805	KRAS G12C mutant protein inhibitor A-1
	KRAS G12C mutant protein inhibitor A-1 可用于 Ras 相关研究。
T11224	Rineterkib ERK-IN-1	ERK; Raf	MAPK
	Rineterkib (ERK-IN-1) 是口服有效的RAF 和ERK1/2的抑制剂，与 KRAS-突变型非小细胞肺癌、BRAF-突变型非小细胞肺癌、KRAS-突变型胰腺癌、KRAS -突变型结肠癌和 KRAS-突变型卵巢癌尤为相关。
T78170	Kras4B G12D-IN-1	Ras	GPCR/G Protein; MAPK
	Kras4B G12D-IN-1为Kras4B G12D的抑制剂，表现出抗癌活性。在降低Kras4B G12D表达的小鼠胚胎成纤维细胞(MEF)中减少Kras蛋白水平。
T15735	Leptomycin B CI 940,LMB,来普霉素B	CRM1; Antibiotic; Antifungal	Membrane transporter/Ion channel; Microbiology/Virology
	Leptomycin B (LMB) 是一种抗真菌抗生素，可阻断真核细胞周期，抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使 CRM1/exportin 1失活。它
T79147	KRAS degrader-1
	KRAS degrader-1（compound 1）是通过自噬-溶酶体途径降解特定蛋白的高效KRAS降解剂。
T79162	SOS1/KRAS-IN-1	Ras	GPCR/G Protein; MAPK
	SOS1/KRAS-IN-1(Compound 2)为针对SOS1/KRAS介导的疾病进行研究而设计的抑制剂。
T13844	PROTAC K-Ras Degrader-1	Ras	GPCR/G Protein; MAPK
	PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
T79072	KRAS G12D modulator-1	Ras	GPCR/G Protein; MAPK
	KRAS G12D modulator-1（compound 6）是高效KRAS G12D调节剂，NEA-G12D、PPI-G12D 和 pERK-AGS的IC50范围为1-10 μM，适用于癌症研究。
T9533	BC-LI-0186 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) 是选择性抑制亮氨酸 tRNA 合成酶与 Ras 相关的 GTP 结合蛋白 D 相互作用(IC50=46.11 nM)。BC-LI-0186能有效抑制肿瘤相关 MTOR 突变体的特性和雷帕霉素耐药癌细胞的生长，能够用于肺癌的相关研究。
T74973	KRas G12R inhibitor 1
	KRas G12R inhibitor 1 (compound 3) 是一种 KRas G12R 选择性共价抑制剂，可以利用突变半胱氨酸的强亲核性，在 K-Ras 的 Switch II 区域不可逆结合。KRas G12R inhibitor 1 可用于癌症研究。
T18054	K-Ras ligand-Linker Conjugate 1	Others	Others
	K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PROTAC K-Ras Degrader-1, a highly effective K-Ras degrader that achieves ≥70% degradation efficacy in SW1573 cells[1].
T11735	K-Ras G12C-IN-1	Phosphatase	Metabolism
	K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.
T77926	PROTAC KRAS G12C degrader-1	PROTACs	PROTAC
	PROTACKRAS G12C degrader-1是基于Cereblon的KRASG12C PROTAC降解剂，能诱导CRBN/KRASG12C二聚化，并在报告细胞中降解GFP-KRASG12C。
T77802	KRAS G12C inhibitor 1R
	KRAS G12C inhibitor 1R 可用于 Ras 相关研究。
T11282	FGTI-2734	Transferase	Metabolism
	FGTI-2734 是有效的RAS C-末端法尼基转移酶 (FT) 和香叶烯基转移酶-1 (GGT-1) 抑制剂，IC50s 分别为 250 nM 和 520 nM。它可以阻断 KRAS 的膜定位，从而解决 KRAS 耐药性问题，并抑制突变的 KRAS 胰腺肿瘤。
T12979	BI-3406	p38 MAPK; MAPK; Ras	GPCR/G Protein; MAPK
	BI-3406 是一种可口服、高效且选择性的 KRAS-SOS1 抑制剂，具有抗癌活性。它有效减少 GTP 加载的 KRAS 的形成，抑制 MAPK 信号通路。它还抑制 KRAS 与 SOS1之间相互作用，IC50为 6 nM。
T81263	RMC-7977	Ras	GPCR/G Protein; MAPK
	RMC-7977是一种可逆的三重复合RAS抑制剂，对KRAS、NRAS和HRAS的突变型及野生型(WT)变体表现出广谱活性。该化合物能够引发肿瘤消退，在多种依赖RAS的临床前癌症模型中显示出良好的耐受性。此外，RMC-7977还能有效抑制KRASG12C癌瘤模型的生长。[1]
T7123	AMG-47a	VEGFR; p38 MAPK; JAK; Src	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors
	AMG-47a 是具有口服活性的 Lck 抑制剂，IC50值为 0.2 nM。它具有抗炎作用，对 VEGF2、p38α、p38α、Jak3、MLR 和 IL-2的 IC50值分别为 1、3、72、30 和 21 nM。
T6843	GDC-0623 G-868,GDC0623,RG 7421,MEK inhibitor 1	Apoptosis; MEK	Apoptosis; MAPK
	GDC-0623 (RG 7421) 是一种 ATP 竞争性的MEK1抑制剂，Ki 值为 0.13 nM。它对 A375 细胞中 BRAFV600E 的 EC50值为 7 nM，而对 HCT116 细胞中 KRAS (G13D)的 EC50值为 42 nM。
T74698	RMC-6236 RAS-IN-2
	RMC-6236是一种相关的 RAS（ON）多选择性抑制剂，对CypA蛋白(KD1)的亲和力为55.3 nmol/L，RMC-6236对KRAS突变癌细胞系HPAC (KRASG12D/WT, PDAC)和Capan-2 (KRASG12V/WT, PDAC)， EC50分别为1.2和1.4 nmol/L，可用于癌症治疗。[1,2]
T6878	LJI308	S6 Kinase	MAPK; PI3K/Akt/mTOR signaling
	LJI308 是泛RSK 抑制剂，对 RSK1、RSK2 和 RSK3 的IC50分别为 6、4 和 13 nM。它抑制辐照、EGF 处理和表达 KRAS 突变的细胞中 RSK (T359/S363) 和 YB-1 (S102) 的磷酸化。
T37130	MRTX1133 formic
	MRTX1133 is a highly selective, first-in-class inhibitor of KRAS G12D. MRTX1133 targets the KRAS G12D protein in both active and inactive states. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells[1][2]. MRTX1133 demonstrates dose-dependent inhibition of the KRAS pathway tumor regression in G12D mutant tumor models[2]. [1]. Xiaolun Wang, et al.Kras g12d inhibitors.WO2021041671A1.[2]. KRAS G12D Inhibitor: MRTX1133. [(accessed on 22 April 2021)];2021 Available onli...
T62566	KRAS G12C inhibitor 53
	KRAS G12C inhibitor 53 (Compound 1) 是一种 KRAS G12C 抑制剂。
T11768	KRAS G12C inhibitor 14	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 14 是一种有效的 KRAS G12C 抑制剂（IC50= 18 nM）。
T64085	KRAS G12C inhibitor 43
	KRAS G12C inhibitor 43 是 KRAS G12C 的有效抑制剂，能够抑制 H358 细胞 (IC50: 0.001-1 μM μM)、 A549 细胞 (IC50>1 μM)、 HCC 细胞 (IC50>1 μM) 的迁移和增殖。
T79057	KRAS G12C inhibitor 58	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 58作为KRAS G12C的抑制剂，专门用于癌症领域的研究应用。
T79799	pan-KRAS-IN-4	Ras	GPCR/G Protein; MAPK
	Pan-KRAS-IN-4 (compound 5) 为一种高效KRAS抑制剂，其IC50值分别为0.37 nM (Kras G12C) 和0.19 nM (Kras G12V)。
T72335	KRAS G12C inhibitor 32	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 32，一种含有八个原子的N杂环化合物，作为KRAS G12C的有效抑制剂。
T79092	TH-Z827	Ras	GPCR/G Protein; MAPK
	TH-Z827为特异性针对KRAS(G12D)突变的抑制剂，IC50值为2.4 μM。此化合物不与KRAS(WT)或KRAS(G12C)结合，并可抑制KRAS(G12D)与CRAF的相互作用，其IC50值为42 μM。
T79148	PROTAC KRAS G12C degrader-3	Ras	GPCR/G Protein; MAPK
	PROTACKRAS G12C degrader-3（Comp 283）是一种癌症研究中使用的高效KRAS G12C降解剂。
T72599	KRAS inhibitor-11
	KRAS inhibitor-11 是一种 KRAS 抑制剂。
T79814	pan-KRAS-IN-3	Ras	GPCR/G Protein; MAPK
	Pan-KRAS-IN-3 (Example 84)为一款pan-KRAS抑制剂，适用于癌症研究领域。
T36676	Rineterkib hydrochloride
	Rineterkib hydrochloride (compound B) is an orally active RAF and ERK1/2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer[1]. ERK-IN-1 (compound B) (50, 75 mg/kg, p.o., qd/q2d, 27 days) treatment significantly reduces the tumor volume in the C...
T74607	KRAS G12D inhibitor 15
	KRAS G12D inhibitor 15 是一种有效的 KRAS G12D 抑制剂。KRAS G12D inhibitor 15 具有研究各种疾病或病症的潜力，例如癌症或癌症转移。
T73864	Deltasonamide 1 TFA
	Deltasonamide 1 TFA 是一种PDE6δ-KRas 抑制剂。Deltasonamide 1 可以抑制 PDE6δ-KRas，KD 为 203 pM。Deltasonamide 1 可用于肿瘤的研究。
T79800	pan-KRAS-IN-2	Ras	GPCR/G Protein; MAPK
	Pan-KRAS-IN-2（compound 6）是一种抑制剂，对KRAS WT及其多种突变体（G12D、G12C、G12V、G12S、G12A、Q61H）表现出极高的抑制活性，其IC50均不超过10 nM；然而对KRAS G13D的抑制活性较低，IC50超过10 μM。
T79166	KRAS G12C inhibitor 60	Ras	GPCR/G Protein; MAPK
	KRAS G12C inhibitor 60 (compound 23)作为一种高效的Kras-G12C抑制剂, 主要应用于肺癌、结直肠癌和胰腺癌的研究领域。
TP2116	SAH-SOS1A
	KRas/son of sevenless 1 (SOS1) interaction inhibitor. Binds within nucleotide binding pocket of KRas (Kd values are 106 - 176 nM for wild type KRas and various KRas mutants). Inhibits nucleotide binding to KRas in a concentration dependent manner. Display
T78651	Glecirasib JAB-21822,KRAS G12C inhibitor 36	Ras	GPCR/G Protein; MAPK
	Glecirasib (KRAS G12C inhibitor 36) 作为潜在的KRAS G12C抑制剂，在Ras蛋白家族中发挥作用，对细胞内信号传递具重要影响，并在生长发育中扮演关键角色。本化合物显示出研究KRAS G12C介导的癌症潜力。
T72336	KRAS G12C inhibitor 45
	KRAS G12C inhibitor 45 是一种有效的KRAS G12C 抑制剂。
T36761	KRAS inhibitor-10
	KRAS inhibitor-10 (WO2021005165 A1, compound 11) is a potent and selective inhibitor of RAS proteins, with a specific focus on KRAS proteins. This orally active anti-cancer agent demonstrates strong efficacy in cancer research, specifically in pancreatic cancer, breast cancer, multiple myeloma, leukemia, and lung cancer. KRAS inhibitor-10 is classified as a tetrahydroisoquinoline compound. Its inhibitory properties provide valuable insights and potential therapeutic applications in the field of ...
T82352	GADGVGKSAL
	GADGVGKSAL为KRAS G12D突变型10mer肽，具有免疫原性，常用作癌症免疫疗法研究中的新型抗原。
T62751	KRAS inhibitor-12
	KRAS inhibitor-12 (compound 6-1) 是一种 KRAS G12C 的有效抑制剂 (IC50: 0.537 μM)。KRAS inhibitor-12 在 MIA PaCA-2，A549 细胞中表现出 p-ERK 抑制作用，其 IC50 值分别为 1.3，3.7 μM。 KRAS inhibitor-12 具有潜力进行胰腺癌，结直肠癌和肺癌的研究。
T79673	LUNA18	Ras	GPCR/G Protein; MAPK
	LUNA18作为口服活性KRAS抑制剂，其对KRASG12D-SOS的IC50值<2 nM，适用于癌症研究。
T82349	GAGGVGKSA
	GAGGVGKSA，作为wild-type KRAS G12D 9mer肽，具有免疫原性，可用于研究癌症免疫疗法中新抗原的应用。
T74663	KRAS G12D inhibitor 17
	KRAS G12D inhibitor 17 (example 8) 是一种喹唑啉连接 (4R)-4-羟基-l -脯氨酸酰胺化合物，可诱导 G12D 突变 KRAS 蛋白降解。KRAS G12D inhibitor 17 是一种 PTOTAC。

化合物

KRAS mutant protein inhibitor 1

Cat.No: T40272

KRAS G12D inhibitor 1

Cat.No: T9674

KRas G12C inhibitor 1

Cat.No: T11776

Target: Ras

Cat.No: T8418

Target: Others

KRAS G12C mutant protein inhibitor A-1

Cat.No: T77805

Cat.No: T11224

Synonym: ERK-IN-1

Target: ERK, Raf

Kras4B G12D-IN-1

Cat.No: T78170

Target: Ras

Cat.No: T15735

Synonym: CI 940,LMB,来普霉素B

Target: CRM1, Antibiotic, Antifungal

KRAS degrader-1

Cat.No: T79147

SOS1/KRAS-IN-1

Cat.No: T79162

Target: Ras

PROTAC K-Ras Degrader-1

Cat.No: T13844

Target: Ras

KRAS G12D modulator-1

Cat.No: T79072

Target: Ras

Cat.No: T9533

Synonym: 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide

Target: Others

KRas G12R inhibitor 1

Cat.No: T74973

K-Ras ligand-Linker Conjugate 1

Cat.No: T18054

Target: Others

K-Ras G12C-IN-1

Cat.No: T11735

Target: Phosphatase

PROTAC KRAS G12C degrader-1

Cat.No: T77926

Target: PROTACs

KRAS G12C inhibitor 1R

Cat.No: T77802

Cat.No: T11282

Target: Transferase

Cat.No: T12979

Target: p38 MAPK, MAPK, Ras

Cat.No: T81263

Target: Ras

Cat.No: T7123

Target: VEGFR, p38 MAPK, JAK, Src

Cat.No: T6843

Synonym: G-868,GDC0623,RG 7421,MEK inhibitor 1

Target: Apoptosis, MEK

Cat.No: T74698

Synonym: RAS-IN-2

Cat.No: T6878

Target: S6 Kinase

MRTX1133 formic

Cat.No: T37130

KRAS G12C inhibitor 53

Cat.No: T62566

KRAS G12C inhibitor 14

Cat.No: T11768

Target: Ras

KRAS G12C inhibitor 43

Cat.No: T64085

KRAS G12C inhibitor 58

Cat.No: T79057

Target: Ras

pan-KRAS-IN-4

Cat.No: T79799

Target: Ras

KRAS G12C inhibitor 32

Cat.No: T72335

Target: Ras

Cat.No: T79092

Target: Ras

PROTAC KRAS G12C degrader-3

Cat.No: T79148

Target: Ras

KRAS inhibitor-11

Cat.No: T72599

pan-KRAS-IN-3

Cat.No: T79814

Target: Ras

Rineterkib hydrochloride

Cat.No: T36676

KRAS G12D inhibitor 15

Cat.No: T74607

Deltasonamide 1 TFA

Cat.No: T73864

pan-KRAS-IN-2

Cat.No: T79800

Target: Ras

KRAS G12C inhibitor 60

Cat.No: T79166

Target: Ras

Cat.No: TP2116

Cat.No: T78651

Synonym: JAB-21822,KRAS G12C inhibitor 36

Target: Ras

KRAS G12C inhibitor 45

Cat.No: T72336

KRAS inhibitor-10

Cat.No: T36761

Cat.No: T82352

KRAS inhibitor-12

Cat.No: T62751

Cat.No: T79673

Target: Ras

Cat.No: T82349

KRAS G12D inhibitor 17

Cat.No: T74663

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His) KRAS1,K-RAS4B,Kirsten rat sarcoma viral on...	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. It binds ...
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His) NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-RAS2B,K-RAS,Kirsten...	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. It binds ...
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His) Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. It binds ...
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His) KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. It binds ...
TMPY-06138	KRAS Protein, Human, Recombinant (61Q, His) Kirsten rat sarcoma viral oncogene homolog,K-RAS2B,NS3,K-RAS...	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. It binds ...
TMPY-06345	KRAS Protein, Human, Recombinant (His & Avi), Biotinylated RASK2,K-RAS2A,RALD,C-K-RAS,NS3,Kirsten rat sarcoma viral onc...	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Once it is turned on it recruits and activates proteins necessary for the propagation of growth factor and other receptors' signal, such as c-Raf and PI 3-kinase. It binds ...
TMPU-00001	KRAS Protein, Human, Recombinant (G12S, GST) NS,C-K-RAS,K-RAS2A,KRAS1,K-RAS2B,KRAS<...	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. K-Ras functions as a molecular on/off switch. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events b...
TMPY-03487	NRAS Protein, Human, Recombinant (His) NS6,NCMS,CMNS,neuroblastoma RAS viral (v-ras) oncogene homol...	Human	E. coli
	NRAS was discovered by researchers at the Institute of Cancer Research, funded by the Cancer Research Campaign (now Cancer Research UK). NRAS gene is a member of the Ras gene family. It is mapped on chromosome 1, and it is activated in HL6, a promyelocytic leukemia line. The mammalian ras gene family consists of the Harvey and Kirsten ras genes (HRAS and KRAS), an inactive pseudogene of each (c-Hras2 and c-Kras1), and the N-ras gene. They differ significantly only in the C-terminal 4 amino acids...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus-Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-00664	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Angiopoietin-2,AGPT2,angiopoietin 2,ANG2	Human	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine kinase receptor, Tie-2, found primarily on the luminal surface of endothelial cells. ANG-2's role in angiogenesis generally is considered as an antagonist for ANG1, inhibiting ANG1-promoted Tie2 signaling, which is critical for blood vessel maturation and stabilization. ANG-2 mod...
TMPY-01298	CADM1 Protein, Human, Recombinant (His) Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC-	Human	HEK293
	Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular domain of IGSF4 and mediate homophilic or heterophilic interactions independently of Ca2+. The cytoplasmic domain of IGSF4 contains the binding motifs that connect to actin fibers. Since IGSF4 has been characterized by several independent research groups, this molecule is called...
TMPY-04779	BTN3A2 Protein, Human, Recombinant (His) BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...	Human	HEK293
	The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted...
TMPY-03363	C-Reactive Protein Protein, Human, Recombinant C-Reactive Protein,C-reactive protein, pentraxin-related,PTX...	Human	HEK293
	C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monit...
TMPY-02512	Alpha-Synuclein Protein, Human, Recombinant PD1,α-Synuclein,PARK4,synuclein, α (non A4 componen...	Human	E. coli
	Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the...
TMPY-05354	CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated CD28 molecule,Tp44	Human	HEK293
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc) 1810061I13Rik,Clec2,C-ty...	Mouse	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and...
TMPY-04824	CTLA-4 Protein, Human, Recombinant CTLA-4,GSE,IDDM12,CELIAC3,ALPS5,CD,GRD4,cytotoxic T...	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role i...
TMPY-00986	IL-34 Protein, Mouse, Recombinant (His) interleukin 34,2010004A03Rik,AI593503	Mouse	HEK293
	IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). IL-34 protein is expressed in various tissues, including heart, brain, lung, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and most abundant in the spleen. The colon...
TMPY-03273	IL-18 Protein, Mouse, Recombinant interleukin 18,白细胞介素,白介素,Il-18,Igif	Mouse	E. coli
	Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi...
TMPY-02412	ENO1 Protein, Human, Recombinant (His) PPH,NNE,enolase 1, (alpha),ENO1L1...	Human	E. coli
	The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make ...
TMPY-01055	IL-4R Protein, Human, Recombinant (His) interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ...
TMPY-01912	Cadherin 17/CDH17 Protein, Human, Recombinant (His) HPT-1,cadherin 17, LI cadherin (liver-inte...	Human	HEK293
	Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-01834	CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) CD16,Fc receptor, IgG, low affinity III	Mouse	HEK293
	Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as...
TMPY-01608	Decorin Protein, Human, Recombinant (His) PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role...
TMPY-00843	IL-25/IL17E Protein, Human, Recombinant (hFc) interleukin 25,IL17E	Human	HEK293
	Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–produ...
TMPY-05277	IL-4R Protein, Human, Recombinant (hFc) IL4R,IL4RA,CD124,IL-4RA,interleukin 4 receptor	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ...
TMPY-04810	CD47 Protein, Mouse, Recombinant (His) AA407862,CD47 molecule,AW108519,91	Mouse	HEK293
	CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b...
TMPY-01280	FOLR2 Protein, Human, Recombinant (His) FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...	Human	HEK293
	Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPY-01462	IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) interleukin 11 receptor subunit alpha,hCG_...	Human	HEK293
	Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increas...
TMPY-03256	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His) KLR,killer cell lectin-like receptor subfamily K, member	Human	Baculovirus-Insect Cells
	KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stim...
TMPY-05579	PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated PRR1,ED4,PVRR,nectin-1,OFC7,SK-12...	Human	HEK293
	Poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin-1; CD111), also known as PVRL1 is a cell adhesion molecule belonging to the immunoglobulin superfamily that can bind to virion glycoprotein D (gD) to mediate entry of herpes simplex viruses (HSV) and pseudorabies virus (PRV). CD111/Nectin-1/PVRL1 colocalizes with E-cadherin at adherens junctions in epithelial cells. The disruption of cell junctions can result in the redistribution of nectin-1. To determine whether disruption of ...
TMPY-00939	Thrombopoietin Protein, Mouse, Recombinant (His) thrombopoietin,Mpllg,Tpo,Mgdf,Ml	Mouse	HEK293
	Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. Thrombopoietin protein stimulates both proliferation of progenitor megakaryocytes and their maturation to platelet-producing megakaryocytes, and also accelerates the recovery of platelets. Thrombopoietin...
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) angiopoietin 1,AGPT,AGP1,ANG1	Human	HEK293
	The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In disease, ANGPT2-mediated inhibition of TIE2 in blood vessels is linked to vascular leak, inflammation, and metastasis. Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide and is caused by developmental defects in 2 aqueous humor outflow structures...
TMPY-03762	E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc) cadherin 1, type 1, E-cadherin (epithelial...	Human	HEK293
	Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadherin (E-Cad), also known as CDH1 and CD324, is a calcium-dependent cell adhesion molecule the intact function of which is crucial for the establishment and maintenance of epithelial tissue polarity and structural integrity. Mutations in CDH1 occur in diffuse type gastric cancer, lo...
TMPY-01431	L1CAM Protein, Human, Recombinant (His) N-CAM-L1,MASA,HSAS,L1 cell adhesion molecu...	Human	HEK293
	L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brain cells, in recent years L1-CAM has been detected in other tissues, and a variety of cancer cells, including some common types of human cancer. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan, and integrins, and it has been revealed that the RGD motif ...
TMPY-01701	IL-12RB1 Protein, Human, Recombinant (His) interleukin 12 receptor, β1,IL12R...	Human	HEK293
	Interleukin 12 receptor, beta 1 is also known as IL-12 receptor beta component, IL-12R subunit beta-1, and CD212 antigen (CD212). IL12RB1(CD212) is a subunit of the interleukin 12 receptor. IL12RB1(CD212) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukin 12 (IL12) with a low affinity and is thought to be a part of the IL12 receptor complex. IL12RB1(CD212) forms a disulfide-linked oligomer, which is required for its IL12 bind...
TMPY-01907	VSIG4 Protein, Human, Recombinant (His) Z39IG,CRIg,V-set and immunoglobulin domain containing 4	Human	HEK293
	VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that a...
TMPY-02115	R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His) CRISTIN1,THSD2,R-spondin 3,PWTSR	Human	HEK293
	R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s...
TMPY-04793	IL-35 Protein, Human, Recombinant (Flag & His) NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NFSK,IL-	Human	HEK293
	IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A, together with IL27B, form a disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and T...
TMPY-06076	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like...	Human	HEK293
	LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophag...
TMPY-02105	SCF Protein, Mouse, Recombinant (His) Gb,Kitlg,SF,Clo,Mgf,SLF,Sl,KIT ligand,SCF,Con	Mouse	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in ...
TMPY-00828	Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His) MPS2,IDS,SIDS,iduronate 2-sulfatase	Human	HEK293
	Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an...
TMPY-00991	LIFR Protein, Human, Recombinant (His) STWS,CD118,SJS2,LIF-R,leukemia inhibitory ...	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus affects the differentiation, proliferation, and survival of a wide variety of cells in the adult and the embryo. Besides LIF, LIFR can also bind to and activate CNTF (ciliary neurotrophic factor) and CLC (Cardiotrophin Like Cytokine). Evidence showed that in the retina, LIFR activat...
TMPY-03630	MZB1/PERP1 Protein, Human, Recombinant (His) MEDA-7,marginal zone B and B1 cell-specific protein...	Human	HEK293
	MZB1 (Marginal Zone B And B1 Cell Specific Protein, also known as MEDA-7 and pERp1) is a Protein Coding gene. MZB1 is a B-cell-specific and endoplasmic reticulum (ER)-localized protein implicated in antibody secretion and integrin-mediated cell adhesion. MZB1 is important for B cell function as a key regulator of antibody secretion, calcium homeostasis, and adhesion. MZB1 may play a central role in B cell neoplasms and is a potential target for future therapeutic interventions. Low MZB1 expressi...
TMPY-05566	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) CD22 molecule,SIGLEC-2,SIGLEC2	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. In addition to its potential role as a mediator of intercellular interactions, signal transduction through CD22 can activate B cells and modulate antigen receptor signaling in vitro. ...
TMPY-06051	SIRP alpha Protein, Human, Recombinant (hFc) signal-regulatory protein alpha,SIRP alpha,PTPNS1,P...	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antigen-like family member A, SIRPA and CD172a, is a single-pass type I membrane protein which contains two Ig-like C1-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIRPA is ubiquitously expressed. It is highly expressed in brain and detected ...
TMPY-01410	IL-3R alpha/CD123 Protein, Human, Recombinant (His) CD123,interleukin 3 receptor, alpha (low affinity),...	Human	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subfamily. The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. The WSXWS motif of IL3RA appears to be necessary for prop...
TMPY-00908	Renin Protein, Human, Recombinant (His) REN,renin,FLJ10761,HNFJ2	Human	HEK293
	Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angio...
TMPY-04956	HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated MDA-BF-1,c-erbB-3,HER3,p85-sErbB3,LCCS2,p1...	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
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重组蛋白

KRAS Protein, Human, Recombinant (G12D, His)

Cat.No: TMPY-06056

Species: Human

Expression System: E. coli

KRAS Protein,Human,Recombinant(G12C & Q61H, His)

Cat.No: TMPY-04116

Species: Human

Expression System: E. coli

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Cat.No: TMPY-04113

Species: Human

Expression System: E. coli

KRAS Protein,Human, Recombinant (Q61H, His)

Cat.No: TMPY-01888

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (61Q, His)

Cat.No: TMPY-06138

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06345

Species: Human

Expression System: E. coli

KRAS Protein, Human, Recombinant (G12S, GST)

Cat.No: TMPU-00001

Species: Human

Expression System: E. coli

NRAS Protein, Human, Recombinant (His)

Cat.No: TMPY-03487

Species: Human

Expression System: E. coli

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus-Insect Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03745

Species: Human

Expression System: HEK293

ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00664

Species: Human

Expression System: HEK293

CADM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01298

Species: Human

Expression System: HEK293

BTN3A2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04779

Species: Human

Expression System: HEK293

C-Reactive Protein Protein, Human, Recombinant

Cat.No: TMPY-03363

Species: Human

Expression System: HEK293

Alpha-Synuclein Protein, Human, Recombinant

Cat.No: TMPY-02512

Species: Human

Expression System: E. coli

CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-05354

Species: Human

Expression System: HEK293

CLEC-2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00586

Species: Mouse

Expression System: HEK293

CTLA-4 Protein, Human, Recombinant

Cat.No: TMPY-04824

Species: Human

Expression System: HEK293

IL-34 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00986

Species: Mouse

Expression System: HEK293

IL-18 Protein, Mouse, Recombinant

Cat.No: TMPY-03273

Species: Mouse

Expression System: E. coli

ENO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02412

Species: Human

Expression System: E. coli

IL-4R Protein, Human, Recombinant (His)

Cat.No: TMPY-01055

Species: Human

Expression System: HEK293

Cadherin 17/CDH17 Protein, Human, Recombinant (His)

Cat.No: TMPY-01912

Species: Human

Expression System: HEK293

CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)

Cat.No: TMPY-01834

Species: Mouse

Expression System: HEK293

Decorin Protein, Human, Recombinant (His)

Cat.No: TMPY-01608

Species: Human

Expression System: HEK293

IL-25/IL17E Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00843

Species: Human

Expression System: HEK293

IL-4R Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05277

Species: Human

Expression System: HEK293

CD47 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04810

Species: Mouse

Expression System: HEK293

FOLR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01280

Species: Human

Expression System: HEK293

IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)

Cat.No: TMPY-01462

Species: Human

Expression System: HEK293

NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)

Cat.No: TMPY-03256

Species: Human

Expression System: Baculovirus-Insect Cells

PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated

Cat.No: TMPY-05579

Species: Human

Expression System: HEK293

Thrombopoietin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00939

Species: Mouse

Expression System: HEK293

ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05435

Species: Human

Expression System: HEK293

E-Cadherin/Cadherin-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03762

Species: Human

Expression System: HEK293

L1CAM Protein, Human, Recombinant (His)

Cat.No: TMPY-01431

Species: Human

Expression System: HEK293

IL-12RB1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01701

Species: Human

Expression System: HEK293

VSIG4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01907

Species: Human

Expression System: HEK293

R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)

Cat.No: TMPY-02115

Species: Human

Expression System: HEK293

IL-35 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-04793

Species: Human

Expression System: HEK293

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06076

Species: Human

Expression System: HEK293

SCF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02105

Species: Mouse

Expression System: Baculovirus-Insect Cells

Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)

Cat.No: TMPY-00828

Species: Human

Expression System: HEK293

LIFR Protein, Human, Recombinant (His)

Cat.No: TMPY-00991

Species: Human

Expression System: HEK293

MZB1/PERP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03630

Species: Human

Expression System: HEK293

Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)

Cat.No: TMPY-05566

Species: Human

Expression System: HEK293

SIRP alpha Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06051

Species: Human

Expression System: HEK293

IL-3R alpha/CD123 Protein, Human, Recombinant (His)

Cat.No: TMPY-01410

Species: Human

Expression System: HEK293

Renin Protein, Human, Recombinant (His)

Cat.No: TMPY-00908

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04956

Species: Human

Expression System: HEK293

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